Long term stability of adsorption of Der s1 allergen onto alum at different phosphate ion concentrations
نویسندگان
چکیده
Background Allergen adsorption onto alum is relevant for safety and immunogenicity of alum-adjuvanted allergen vaccines, used for subcutaneous immunotherapy. Adsorption of the Group 1 Mite allergens can be impaired by phosphate buffers. On the other hand, diminishing or abolishing buffer salts can affect long term stability. Alum content can also influence immunogenicity and adsorption, as well as, stability.
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